Plexus Probio5 Review

Plexus Probio5 Review (New 2020) – Safe and Effective Digestion Support?


Plexus Probio5 Review 

Our fast lifestyles can lead to an array of health problems, some of which can be truly serious and persistent, and most of them tend to stem from the digestive system. A few of the most common digestive problems include bloating, abdominal pain, change in bowel habits, and the like. These type of issues not only prevent users from maintaining a healthy life, but they also induce pain, discomfort, and humiliation.

Rather than applying ineffective remedies to one’s lifestyle or choosing products that have low-grade ingredients, a better approach may be to opt for an effective and safe formula.

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Plexus Probio5 is a popular digestive support formula that promises to resolve the common digestion problems most of us face on regular basis. The manufacturers state they included 5 of the best strains of probiotic bacteria that are said to not only aid in digestion but also support immune system function and overall health. Plexus Probio5 also contains various enzymes that help with the breakdown of nutrients that we consume daily.

The product comes in a capsule form, which means that the ingredients within the capsule will dissolve immediately upon digestion, allowing individuals to experience rapid results so that they can get the full relief they deserve.
All of this sounds fine and dandy, however, is everything said here true? Continue reading and find out!

How Does Plexus Probio5 Work?

The reason why the Plexus Probio5 formula claims to be so effective is due to the superior probiotic complex that it features. This probiotic complex can create new spores. Products similar to this one only offer bacteria that helps to clean up the unhealthy and damaging particles in the intestines. To support bacteria, consumers often take a prebiotic, which acts as a food.

The difference between Plexus Probio5 and other remedies is that the bacteria in the Plexus 5 strain formula helps to spawn more bacteria in the process. With this expansion, the body will be filled with healthy bacteria that improves immune system function and overall digestion. Plexus Probio5 also contains digestive enzymes that help in the breakdown of food, which enhances the absorption of nutrients.

Plexus Probio5 Ingredients

Besides Vitamin C, B6 and Grape Seed Extract, which are the only ingredients with actual dosing information, the rest of Plexus Probio5 is just one big proprietary blend.

Unfortunately, proprietary blends are always a bad sign. Supplement companies use these blends to mix different ingredients together, providing no clear dosing indication. With no clear dosing information Plexus Probio5 increases the risk of side effects and inefficiency.

Nonetheless, here is the list of ingredients included in Plexus Probio5:

  1. Vitamin C – Offers a wide range of benefits, including protection against immune system deficiencies, prenatal health problems, cardiovascular disease, and even eye infections (1). Recent research done on Vitamin C looked at over 10 years of research concluded on this vitamin. They went over all the benefits Vitamin C provides, from lowering high blood pressure to cancer prevention, Vitamin C is truly the ideal nutrient. Most of us don’t get enough Vitamin C during the day, that’s why supplementing it is a great idea (2).
  2. Vitamin B6 – Plays various important roles in the human body. Vitamin B6 boosts one’s metabolism, liver function, nerve function, and provides extra energy during the course of the day (3). Research shows that Vitamin B6 deficiencies result in lower testosterone levels, which makes the vitamin crucial for healthy testosterone production (4).

Proprietary Enzyme Blend:

  1. Proteases – Is an essential enzyme necessary for normal gut health. Proteases is generally known for its role in the digestion of dietary protein, however, its properties go far beyond (5).
  2. Chitosanase – Represents a unique and powerful enzyme that breaks down chitin, an important part of the structure of cell walls (6).
  3. Cellulase – Supports Chitosanase and enhances its activity by supporting the breakdown of the cellulose component of cell walls. This should allow a higher nutrient absorption rate (7).
  4. Serrapeptase – Has similar properties like the previous enzymes. It enhances nutrient absorption and allows food to convert into usable antioxidants, vitamins, minerals, etc.

Probiotic Blend:

  1. Bacillus Coagulans – Is a spore bacteria which can have beneficial properties for digestion and immune function (8). Among its abilities, it includes shortening of diarrhea episodes, as well as alleviation of various gastrointestinal issues like Crohn’s disease, Ulcerative colitis, IBS, IBD, etc.
  2. Lactobacillus Acidophilus – This good bacteria transforms milk sugars into lactic acid during food decomposition, therefore enhancing lactose tolerance and removing any abdominal pain, bloating or gas caused by otherwise improper digestion of dairy foods. This bacteria also improve immunity while eradicating harmful pathogens (9).
  3. Bifidobacterium Longum – Has the capacity to boost food decomposition, enhancing nutrient assimilation in the gastrointestinal tract, and improving weight loss and weight management. This probiotic also acts as a natural antimicrobial inside the gut, fighting all harmful substance, pathogens, curing bowel inflammation, Irritable Bowel Syndrome, and more (10).
  4. Lactobacillus Plantarum – This probiotic is best known to suppress Escherichia coli infections, improving the body’s natural food decomposition patterns and reducing the symptoms related to lactose intolerance and sensitivity (11).
  5. Saccharomyces Boulardii – A popular probiotic that enhances digestion and immune protective qualities. Similar to previous probiotics, this one also suppresses any IBS symptoms and helps eradicate any dangerous pathogens and harmful substances (12).
  6. Grape Seed Extract – Holds various health benefits that range from improved eyesight to better diabetes control. Grape Seed provides natural antioxidants that improve digestion, reduce PMS symptoms, better blood pressure and cholesterol. It might even prevent some types of cancer. Long-term use could induce mild side effects (13) (14).

Ingredients Summary

Overall, Plexus Probio5 has a decent foundation of ingredients. The formula uses components that have some science backing up their claims and properties. However, the big problem with this formulation is the dosing information. Without this valuable information, users are put at serious risk of side effects and under or overdosing.
Because of this risk, it is highly advisable to consult a physician or doctor before the use of Plexus Probio5.

Related to Plexus Probio5: Phentaslim Review (New 2020) - Why we rate it as #1


Bottom line, those who are interested in adding a digestive support supplement to their life may want to consider giving Plexus Probio5 a try. This is a potent product that can provide some digestive support, however, it could also induce mild side effects. Additionally, this supplements comes with a 60-day money back guarantee, so if you feel any discomfort or dissatisfaction you can always return it. The product is fairly affordable and it ships out quickly too.


  1. Shailja Chambial, Shailendra Dwivedi, Kamla Kant Shukla, Placheril J. John, and Praveen Sharma. “Vitamin C in Disease Prevention and Cure: An Overview.” Indian J Clin Biochem. (2013 Oct). Viewed at:
  2. Valdés F. “[Vitamin C].” Actas Dermosifiliogr. (2006 Nov). Viewed at:
  3. Bender DA. “Vitamin B6 requirements and recommendations.” Eur J Clin Nutr. (1989 May). Viewed at:
  4. Malouf R, Grimley Evans J. “The effect of vitamin B6 on cognition.” Cochrane Database Syst Rev. (2003).
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  5. Carlos López-Otín, and Judith S. Bond. “Proteases: Multifunctional Enzymes in Life and Disease.” J Biol Chem. (2008 Nov 7). Viewed at:
  6. Enrico Di Cera. “Serine Proteases.” IUBMB Life. (2009 May). Viewed at:
  7. Ramesh Chander Kuhad, Rishi Gupta, and Ajay Singh. “Microbial Cellulases and Their Industrial Applications.” Enzyme Res. (2011). Viewed at:
  8. Mehran Rogha, Mozhdehalsadat Zahiri Esfahani, and Amir Houshang Zargarzadeh. “The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial.” Gastroenterol Hepatol Bed Bench. (2014 Summer). Viewed at:
  9. Alip Borthakur, Ravinder K. Gill, Sangeeta Tyagi, Athanasia Koutsouris, Waddah A. Alrefai, Gail A. Hecht, Krishnamurthy Ramaswamy, and Pradeep K. Dudeja. “The Probiotic Lactobacillus acidophilus Stimulates Chloride/Hydroxyl Exchange Activity in Human Intestinal Epithelial Cells.” J Nutr. (2008 Jul).
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  10. Amy O’Callaghan and Douwe van Sinderen. “Bifidobacteria and Their Role as Members of the Human Gut Microbiota.” Front Microbiol. (2016). Viewed at:
  11. Giselle Nobre Costa,b Francismar Corrêa Marcelino-Guimarães,c Gislayne Trindade Vilas-Bôas,d Tiemi Matsuo,e and Lucia Helena S. Miglioranzaa. “Potential Fate of Ingested Lactobacillus plantarum and Its Occurrence in Human Feces.” Appl Environ Microbiol. (2014 Feb). Viewed at:
  12. Lynne V McFarland. “Systematic review and meta-analysis of Saccharomyces boulardii in adult patients.” World J Gastroenterol. (2010 May 14).  Viewed at:
  13. Feringa HH, Laskey DA, Dickson JE, Coleman CI. “The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials.” J Am Diet Assoc. (2011 Aug). Viewed at:
  14. Ai-Hong Cao, Jian Wang, Hai-Qing Gao, Ping Zhang, and Jie Qiu. “Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques.” J Geriatr Cardiol. (2015 Jul).
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About the Author Emily Robinson

Emily has spent the last 8 years comparing, reviewing and analyzing ingredients in the supplements industry. She has worked extensively with dieticians, nutritionists and personal trainers to separate fact from fiction and help people achieve their fitness goals. In her free time she works and enjoys the outdoors with her husband and 2 children. You can contact her via the "About Us" page.

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